Usually, the donor's bone marrow regenerates completely within 2 to 4 weeks. About 5 percent of the bone marrow is taken from the iliac crest. With bone marrow donation, the risk is essentially limited to the anesthetic. The removal is performed in the prone position and takes about 60 minutes. The resulting wounds are so small that they only require a few stitches or often no stitches at all and heal quickly. Two small incisions in the area of the rear pelvic bone are usually sufficient. In this method, bone marrow is taken from the donor under general anaesthesia using a special syringe from the iliac crest. Long-term side effects are not known according to the current state of research. During the administration of the drug, flu-like symptoms may occur. This procedure has been used at DKMS since 1996. No surgery is necessary, you can usually leave the clinic the same day. The donation takes 4-8 hours on one or two consecutive days. This drug increases the number of stem cells in the peripheral blood, which are then obtained directly from the blood using a special procedure. The donor is administered the growth factor G-CSF for five days. In about 80 percent of the cases the stem cells are taken from the bloodstream. Personal history of cancer (exceptions: Stage 0 or in situ melanoma, breast, bladder, cervical and cured localized skin cancer such as basal cell or squamous cell carcinoma).History of blood clotting or bleeding disorders.Epilepsy or other seizure within one year.Chronic or severe neck or back problems. Diabetes requiring insulin or injectable medication.Sleep apnea, breathing problems or severe asthma (daily inhalers are acceptable).Autoimmune disorders such as lupus, rheumatoid arthritis or multiple sclerosis.History of heart surgery or heart disease.The following medical conditions would prevent a person from registering as a donor or from being cleared to donate. The National Marrow Donor Program has established medical guidelines that we follow to protect the safety of the donor. If you have been diagnosed with any chronic or serious illnesses (whether current or in the past), please check with us before signing up. If you have previously registered with DKMS or another donor center, there is no need to do so again, as you will already be available for searches worldwide. If you are between the ages of 18 and 55-years-old and in general good health, then you may be able to register as a blood stem cell donor.
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